A REVIEW OF NAD+ AND ITS ROLE IN MITOCHONDRIAL FUNCTION

Up coming, we addressed cells with distinct concentrations of NAD+. When included for 24 h at eighty µM in HeLa and four hundred µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Extended Knowledge Fig. 1k,l). Furthermore, 16 µM of NAD+ was adequate to lower fork speed by ~40% in HeLa cells without having impacting th